| 1 |
Title of the course
(L-T-P-C) |
Organic Chemistry (1st Half)
(3-0-0-3) |
| 2 |
Pre-requisite courses(s) |
Fundamental concepts and applications of chemistry (CH 101) |
| 3 |
Course content |
Reactive Intermediates: An overview of the chemistry of carbenes, nitrenes, radicals, carbocations, carbanions and benzynes. Introduction to substitution, elimination, addition, oxidation, reduction, rearrangement types of reactions
Epoxidation named reactions: Jacobsen and Sharpless.
Olefination named reactions: Wittig, Julia, Wharton, Peterson, Tebbe.
Cross-Coupling named reactions: Buchwald-Hartwig, Negishi, Sonogashira, Suzuki, Wurtz, Ullmann, McMurry, Heck, Stille.
Pericyclic reactions: Diels-alder cycloaddition, Ene reaction, Cope rearrangement, Claisen rearrangement (Johnson, Ireland and Eschenmoser).
Organic chemistry in industry: Pharmaceuticals, dye, and agrochemicals
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| 4 |
Texts/References |
- Jerry March and Michael Smith, “Advanced Organic Chemistry”, 7th Ed., Wiley, 2015.
- F. A. Carey and R. J. Sundberg, “Advanced Organic Chemistry, Part A and B”, 5th Ed., Springer, 2008.
- J. Clayden, N. Greeves, and S. Warren, “Organic Chemistry”, 2nd Ed., Oxford University Press, 2014.
- W. Carruthers and I. Coldham, “Modern Methods of Organic Synthesis”, 4th Ed., Cambridge University Press, 2015.
- Laszlo Kurti and Barbara Czako, “Strategic applications of named reactions in organic synthesis”, 1st Ed., Elsevier, 2005.
- R. B. Grossman, “Art of writing reasonable organic reaction mechanisms”, 2nd Ed., Springer, 2010.
- P. Bruice, “Organic Chemistry” 7th Ed., Pearson, 2013.
- Penny Chaloner, “Organic chemistry: A mechanistic approach, CRC Press; 1st edition, 2014
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